Expected outcomes from topical haemoglobin spray in non-healing and worsening venous leg ulcers.

Use of a topical haemoglobin spray for oxygenating pressure ulcers: healing outcomes.

A published evaluation ( Tickle, 2015 ) of the use of a topical haemoglobin spray plus standard care in 18 patients with pressure ulcers showed that, following 4 weeks of treatment, the wound size reduced in 17 wounds and there was a progression toward healing in all 18. All but one of the wounds were over 2 months in duration at baseline. This article reports the results of the healing rates a...

Photoacoustic imaging of real-time oxygen changes in chronic leg ulcers after topical application of a haemoglobin spray: a pilot study.

OBJECTIVE To use a non-invasive measurement of oxygen saturation in chronic leg ulcers after the application of a topical haemoglobin spray to investigate if photoacoustic tomography is able to measure the oxygen saturation and if the stimulated oxygen increase can be demonstrated. METHOD We measured the oxygen saturation of the ulcer tissue in five patients with chronic leg ulcers before app...

Topical haemoglobin – High potential for improved outcomes in chronic venous leg ulcers, based on post hoc analysis and simulation of wound closure outcomes

A topical haemoglobin spray for oxygenating pressure ulcers: a pilot study.

The effect of pressure ulcers on patient quality of life have been recognised as a real problem for many years, and the need for robust and effective management of pressure ulcers is now a prominent national health-care issue. Myriad different interventions exist for the treatment of pressure ulcers, including clinically effective dressings and pressure-relieving devices, yet many pressure ulce...

Topical treatment of chronic venous ulcers with sucralfate: a placebo controlled randomized study.

Venous leg ulcers are an important medical issue due to their high incidence in the elderly and the lack of a standard curative approach. Apart from surgical therapy, different medical treatments to effect ulcer wound repair and regeneration are currently being investigated. Sucralfate is a cytoprotective agent employed to prevent or treat several gastrointestinal diseases such as gastroesophag...